In ZINC since | Heavy atoms | Benign functionality |
---|---|---|
August 29th, 2009 | 20 | Yes |
Popular Name: ethyl ethyl
Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
---|---|---|---|---|---|---|---|---|---|---|
Ref Reference (pH 7) | 2.38 | 6.67 | -10.77 | 0 | 5 | 0 | 64 | 297.376 | 5 | ↓ |
Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
---|---|---|---|---|---|
FKB1A-1-E | FK506-binding Protein 1A (cluster #1 Of 1), Eukaryotic | Eukaryotes | 3100 | 0.39 | Binding ≤ 10μM |
Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
---|---|---|---|---|---|
FKB1A_HUMAN | P62942 | FK506-binding Protein 1A, Human | 3100 | 0.39 | Binding ≤ 10μM |
Description | Species |
---|---|
TGF-beta receptor signaling activates SMADs | |
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) | |
TGFBR1 KD Mutants in Cancer | |
TGFBR1 LBD Mutants in Cancer | |
TGFBR2 Kinase Domain Mutants in Cancer |