| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| September 18th, 2009 | 36 | Yes |
Popular Name: ISOMER A ISOMER A
None
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 2.43 | 8.32 | -21.75 | 3 | 8 | 0 | 103 | 479.54 | 3 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| CALRL-1-E | Calcitonin Gene-related Peptide Type 1 Receptor (cluster #1 Of 1), Eukaryotic | Eukaryotes | 1 | 0.35 | Binding ≤ 10μM |
| CALRL-1-E | Calcitonin Gene-related Peptide Type 1 Receptor (cluster #1 Of 1), Eukaryotic | Eukaryotes | 3 | 0.33 | Functional ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| CALRL_HUMAN | Q16602 | Calcitonin Gene-related Peptide Type 1 Receptor, Human | 1.1 | 0.35 | Binding ≤ 1μM |
| CALRL_HUMAN | Q16602 | Calcitonin Gene-related Peptide Type 1 Receptor, Human | 1.1 | 0.35 | Binding ≤ 10μM |
| CALRL_HUMAN | Q16602 | Calcitonin Gene-related Peptide Type 1 Receptor, Human | 23 | 0.30 | Functional ≤ 10μM |
| Description | Species |
|---|---|
| Calcitonin-like ligand receptors | |
| G alpha (s) signalling events |
