Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.17	14.31	-97.7	2	6	2	34	468.686	11	↓ MOL2 SDF SMILES Flexibase
Hi High (pH 8-9.5)	5.17	9.87	-8.27	0	6	0	31	466.67	11	↓ MOL2 SDF SMILES Flexibase
Mid Mid (pH 6-8)	5.17	12.09	-44.11	1	6	1	33	467.678	11	↓ MOL2 SDF SMILES Flexibase

Clustered Target Annotations
Code	Description	Organism Class	Affinity (nM)	LE (kcal/mol/atom)	Type
5HT1A-1-E	Serotonin 1a (5-HT1a) Receptor (cluster #1 Of 4), Eukaryotic	Eukaryotes	8	0.33	Binding ≤ 10μM
5HT2A-2-E	Serotonin 2a (5-HT2a) Receptor (cluster #2 Of 3), Eukaryotic	Eukaryotes	28	0.31	Binding ≤ 10μM
KCNH2-5-E	HERG (cluster #5 Of 5), Eukaryotic	Eukaryotes	2400	0.23	Binding ≤ 10μM
DRD2-11-E	Dopamine D2 Receptor (cluster #11 Of 24), Eukaryotic	Eukaryotes	27	0.31	Binding ≤ 10μM

ChEMBL Target Annotations
Uniprot	Swissprot	Description	Affinity (nM)	LE (kcal/mol/atom)	Type
DRD2_RAT	P61169	Dopamine D2 Receptor, Rat	27	0.31	Binding ≤ 1μM
5HT1A_RAT	P19327	Serotonin 1a (5-HT1a) Receptor, Rat	8	0.33	Binding ≤ 1μM
5HT2A_RAT	P14842	Serotonin 2a (5-HT2a) Receptor, Rat	28	0.31	Binding ≤ 1μM
DRD2_RAT	P61169	Dopamine D2 Receptor, Rat	27	0.31	Binding ≤ 10μM
KCNH2_HUMAN	Q12809	HERG, Human	2400	0.23	Binding ≤ 10μM
5HT1A_RAT	P19327	Serotonin 1a (5-HT1a) Receptor, Rat	8	0.33	Binding ≤ 10μM
5HT2A_RAT	P14842	Serotonin 2a (5-HT2a) Receptor, Rat	28	0.31	Binding ≤ 10μM

Description	Species
Dopamine receptors	Rattus norvegicus (DRD2_RAT)
G alpha (i) signalling events	Rattus norvegicus (DRD2_RAT)
G alpha (q) signalling events	Rattus norvegicus (5HT2A_RAT)
Serotonin receptors	Rattus norvegicus (5HT2A_RAT)
Voltage gated Potassium channels	Homo sapiens (KCNH2_HUMAN)