| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| October 14th, 2009 | 36 | Yes |
Popular Name: ISOMER A ISOMER A
None
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 2.79 | 8.95 | -22.97 | 3 | 8 | 0 | 103 | 479.54 | 3 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| CALRL-1-E | Calcitonin Gene-related Peptide Type 1 Receptor (cluster #1 Of 1), Eukaryotic | Eukaryotes | 0 | 0.00 | Binding ≤ 10μM |
| CALRL-1-E | Calcitonin Gene-related Peptide Type 1 Receptor (cluster #1 Of 1), Eukaryotic | Eukaryotes | 7 | 0.32 | Functional ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| CALRL_HUMAN | Q16602 | Calcitonin Gene-related Peptide Type 1 Receptor, Human | 0.28 | 0.37 | Binding ≤ 1μM |
| CALRL_HUMAN | Q16602 | Calcitonin Gene-related Peptide Type 1 Receptor, Human | 0.28 | 0.37 | Binding ≤ 10μM |
| CALRL_HUMAN | Q16602 | Calcitonin Gene-related Peptide Type 1 Receptor, Human | 1.3 | 0.35 | Functional ≤ 10μM |
| Description | Species |
|---|---|
| Calcitonin-like ligand receptors | |
| G alpha (s) signalling events |
