Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	-2.63	5.26	-50.84	6	10	1	153	521.62	7	↓ MOL2 SDF SMILES Flexibase
Hi High (pH 8-9.5)	-2.63	5.52	-75.24	5	10	0	155	520.612	7	↓ MOL2 SDF SMILES Flexibase

Clustered Target Annotations
Code	Description	Organism Class	Affinity (nM)	LE (kcal/mol/atom)	Type
THRB-1-E	Prothrombin (cluster #1 Of 8), Eukaryotic	Eukaryotes	22	0.31	Binding ≤ 10μM
TRY2-1-E	Trypsin II (cluster #1 Of 3), Eukaryotic	Eukaryotes	8060	0.20	Binding ≤ 10μM

ChEMBL Target Annotations
Uniprot	Swissprot	Description	Affinity (nM)	LE (kcal/mol/atom)	Type
THRB_HUMAN	P00734	Thrombin, Human	22	0.31	Binding ≤ 1μM
THRB_HUMAN	P00734	Thrombin, Human	22	0.31	Binding ≤ 10μM
TRY2_BOVIN	Q29463	Trypsin II, Bovin	8060	0.20	Binding ≤ 10μM

Description	Species
Cell surface interactions at the vascular wall	Homo sapiens (THRB_HUMAN)
Common Pathway	Homo sapiens (THRB_HUMAN)
G alpha (q) signalling events	Homo sapiens (THRB_HUMAN)
Gamma-carboxylation of protein precursors	Homo sapiens (THRB_HUMAN)
Intrinsic Pathway	Homo sapiens (THRB_HUMAN)
Peptide ligand-binding receptors	Homo sapiens (THRB_HUMAN)
Platelet Aggregation (Plug Formation)	Homo sapiens (THRB_HUMAN)
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-l	Homo sapiens (THRB_HUMAN)
Removal of aminoterminal propeptides from gamma-carboxylated proteins	Homo sapiens (THRB_HUMAN)
Thrombin signalling through proteinase activated receptors (PARs)	Homo sapiens (THRB_HUMAN)
Transport of gamma-carboxylated protein precursors from the endoplasmic reticulu	Homo sapiens (THRB_HUMAN)