In ZINC since | Heavy atoms | Benign functionality |
---|---|---|
October 23rd, 2009 | 39 | No |
Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
---|---|---|---|---|---|---|---|---|---|---|
Ref Reference (pH 7) | 5.15 | 16.87 | -15.73 | 2 | 11 | 0 | 140 | 537.665 | 16 | ↓ |
Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
---|---|---|---|---|---|
CXCR2-1-E | Interleukin-8 Receptor B (cluster #1 Of 2), Eukaryotic | Eukaryotes | 160 | 0.24 | Binding ≤ 10μM |
Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
---|---|---|---|---|---|
CXCR2_HUMAN | P25025 | Interleukin-8 Receptor B, Human | 160 | 0.24 | Binding ≤ 1μM |
CXCR2_HUMAN | P25025 | Interleukin-8 Receptor B, Human | 160 | 0.24 | Binding ≤ 10μM |
Description | Species |
---|---|
Chemokine receptors bind chemokines | |
G alpha (i) signalling events |