Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.06	-0.49	-23.39	3	7	0	106	343.383	3	↓ MOL2 SDF SMILES Flexibase
Hi High (pH 8-9.5)	3.06	1.2	-123.55	1	7	-2	111	341.367	3	↓ MOL2 SDF SMILES Flexibase
Hi High (pH 8-9.5)	3.06	0.43	-71.74	2	7	-1	109	342.375	3	↓ MOL2 SDF SMILES Flexibase
Hi High (pH 8-9.5)	3.06	3.15	-56.76	2	7	-1	113	342.375	3	↓ MOL2 SDF SMILES Flexibase
Hi High (pH 8-9.5)	3.06	2.38	-52.21	3	7	0	110	343.383	3	↓ MOL2 SDF SMILES Flexibase
Mid Mid (pH 6-8)	3.09	3.51	-39.81	3	7	0	107	343.383	4	↓ MOL2 SDF SMILES Flexibase
Mid Mid (pH 6-8)	3.09	2.32	-38.19	4	7	1	104	344.391	4	↓ MOL2 SDF SMILES Flexibase
Lo Low (pH 4.5-6)	3.06	0.57	-111.82	5	7	2	109	345.399	3	↓ MOL2 SDF SMILES Flexibase

Clustered Target Annotations
Code	Description	Organism Class	Affinity (nM)	LE (kcal/mol/atom)	Type
CXCR2-1-E	Interleukin-8 Receptor B (cluster #1 Of 2), Eukaryotic	Eukaryotes	8	0.45	Binding ≤ 10μM
CXCR2-3-E	C-X-C Chemokine Receptor Type 2 (cluster #3 Of 3), Eukaryotic	Eukaryotes	145	0.38	Functional ≤ 10μM
Z80088-1-O	CHO (Ovarian Cells) (cluster #1 Of 4), Other	Other	145	0.38	Functional ≤ 10μM

ChEMBL Target Annotations
Uniprot	Swissprot	Description	Affinity (nM)	LE (kcal/mol/atom)	Type
CXCR2_HUMAN	P25025	Interleukin-8 Receptor B, Human	8	0.45	Binding ≤ 1μM
CXCR2_HUMAN	P25025	Interleukin-8 Receptor B, Human	8	0.45	Binding ≤ 10μM
Z80088	Z80088	CHO (Ovarian Cells)	144.8	0.38	Functional ≤ 10μM
CXCR2_HUMAN	P25025	Interleukin-8 Receptor B, Human	144.8	0.38	Functional ≤ 10μM