| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| October 23rd, 2009 | 30 | No |
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 6.27 | 14.58 | -57.77 | 0 | 6 | -1 | 85 | 413.49 | 15 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| PA24B-1-E | Phospholipase A2 Group 1VB (cluster #1 Of 2), Eukaryotic | Eukaryotes | 46 | 0.34 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| PA24B_HUMAN | P0C869 | Phospholipase A2 Group 1VB, Human | 410 | 0.30 | Binding ≤ 1μM |
| PA24B_HUMAN | P0C869 | Phospholipase A2 Group 1VB, Human | 410 | 0.30 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Acyl chain remodelling of PC | |
| Acyl chain remodelling of PE | |
| Acyl chain remodelling of PG | |
| Acyl chain remodelling of PS | |
| Hydrolysis of LPC | |
| Synthesis of PA | |
| XBP1(S) activates chaperone genes |
