In ZINC since | Heavy atoms | Benign functionality |
---|---|---|
October 24th, 2009 | 42 | No |
Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
---|---|---|---|---|---|---|---|---|---|---|
Ref Reference (pH 7) | 4.66 | 13.47 | -47.08 | 3 | 7 | 1 | 89 | 584.762 | 9 | ↓ |
Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
---|---|---|---|---|---|
BKRB1-1-E | Bradykinin B1 Receptor (cluster #1 Of 1), Eukaryotic | Eukaryotes | 1900 | 0.19 | Binding ≤ 10μM |
BKRB1-1-E | Bradykinin B1 Receptor (cluster #1 Of 1), Eukaryotic | Eukaryotes | 1700 | 0.19 | Functional ≤ 10μM |
Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
---|---|---|---|---|---|
BKRB1_HUMAN | P46663 | Bradykinin B1 Receptor, Human | 1900 | 0.19 | Binding ≤ 10μM |
BKRB1_HUMAN | P46663 | Bradykinin B1 Receptor, Human | 1700 | 0.19 | Functional ≤ 10μM |
Description | Species |
---|---|
G alpha (i) signalling events | |
G alpha (q) signalling events | |
Peptide ligand-binding receptors |