| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| October 24th, 2009 | 20 | No |
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 2.22 | 12.14 | -28.64 | 1 | 2 | 1 | 20 | 286.524 | 15 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| DYN1-1-E | Dynamin-1 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 9360 | 0.35 | Binding ≤ 10μM |
| Z50425-6-O | Plasmodium Falciparum (cluster #6 Of 22), Other | Other | 600 | 0.44 | Functional ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| DYN1_HUMAN | Q05193 | Dynamin-1, Human | 9360 | 0.35 | Binding ≤ 10μM |
| Z50425 | Z50425 | Plasmodium Falciparum | 600 | 0.44 | Functional ≤ 10μM |
| Description | Species |
|---|---|
| EPH-ephrin mediated repulsion of cells | |
| Formation of annular gap junctions | |
| Gap junction degradation | |
| MHC class II antigen presentation | |
| Recycling pathway of L1 | |
| Retrograde neurotrophin signalling | |
| Toll Like Receptor 4 (TLR4) Cascade |
