Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.50	10.15	-130.93	0	4	-2	72	292.356	14	↓ MOL2 SDF SMILES Flexibase
Mid Mid (pH 6-8)	5.50	9	-41.65	1	4	-1	70	293.364	14	↓ MOL2 SDF SMILES Flexibase

Clustered Target Annotations
Code	Description	Organism Class	Affinity (nM)	LE (kcal/mol/atom)	Type
LPAR1-1-E	Lysophosphatidic Acid Receptor Edg-2 (cluster #1 Of 2), Eukaryotic	Eukaryotes	1082	0.44	Binding ≤ 10μM
LPAR3-2-E	Lysophosphatidic Acid Receptor Edg-7 (cluster #2 Of 2), Eukaryotic	Eukaryotes	211	0.49	Binding ≤ 10μM
LPAR1-2-E	Lysophosphatidic Acid Receptor Edg-2 (cluster #2 Of 4), Eukaryotic	Eukaryotes	2300	0.42	Functional ≤ 10μM
LPAR3-1-E	Lysophosphatidic Acid Receptor Edg-7 (cluster #1 Of 3), Eukaryotic	Eukaryotes	422	0.47	Functional ≤ 10μM
Z50587-2-O	Homo Sapiens (cluster #2 Of 9), Other	Other	430	0.47	Functional ≤ 10μM

ChEMBL Target Annotations
Uniprot	Swissprot	Description	Affinity (nM)	LE (kcal/mol/atom)	Type
LPAR3_HUMAN	Q9UBY5	Lysophosphatidic Acid Receptor Edg-7, Human	211	0.49	Binding ≤ 1μM
LPAR1_HUMAN	Q92633	Lysophosphatidic Acid Receptor Edg-2, Human	1082	0.44	Binding ≤ 10μM
LPAR3_HUMAN	Q9UBY5	Lysophosphatidic Acid Receptor Edg-7, Human	211	0.49	Binding ≤ 10μM
Z50587	Z50587	Homo Sapiens	420	0.47	Functional ≤ 10μM
LPAR1_HUMAN	Q92633	Lysophosphatidic Acid Receptor Edg-2, Human	2300	0.42	Functional ≤ 10μM
LPAR3_HUMAN	Q9UBY5	Lysophosphatidic Acid Receptor Edg-7, Human	422	0.47	Functional ≤ 10μM

Description	Species
G alpha (i) signalling events	Homo sapiens (LPAR1_HUMAN)
G alpha (q) signalling events	Homo sapiens (LPAR1_HUMAN)
Lysosphingolipid and LPA receptors	Homo sapiens (LPAR1_HUMAN)