UCSF

Lysophosphatidic Acid Receptor Edg-2, Human (59 Compounds)

Swissprot:
LPAR1_HUMAN
Stitch:
LPAR1_HUMAN
UniProt:
Q92633
ChEMBL:
CHEMBL3819
Reactome:
REACT_19231
REACT_18283
REACT_18365
PDB:
LPAR1

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 59 5 0 0
Binding ≤ 1μM 36 4 0 0
Functional ≤ 10μM 66 7 2 0

Reactome Network (3)

Reactome ID Description Species
REACT_19231 G alpha (i) signalling events Homo sapiens
REACT_18283 G alpha (q) signalling events Homo sapiens
REACT_18365 Lysosphingolipid and LPA receptors Homo sapiens
Uniprot Swissprot Chembl Description Number Shared
LPAR2_HUMAN Q9HBW0 CHEMBL3724 Lysophosphatidic Acid Receptor Edg-4, Human 27
LPAR3_HUMAN Q9UBY5 CHEMBL3250 Lysophosphatidic Acid Receptor Edg-7, Human 68
LPAR5_HUMAN Q9H1C0 CHEMBL5700 Lysophosphatidic Acid Receptor 5, Human 2

G alpha (q) signalling events

Uniprot Swissprot Chembl Description Number Shared
LPAR2_HUMAN Q9HBW0 CHEMBL3724 Lysophosphatidic Acid Receptor Edg-4, Human 27
LPAR3_HUMAN Q9UBY5 CHEMBL3250 Lysophosphatidic Acid Receptor Edg-7, Human 68
LPAR5_HUMAN Q9H1C0 CHEMBL5700 Lysophosphatidic Acid Receptor 5, Human 2

Lysosphingolipid and LPA receptors

Uniprot Swissprot Chembl Description Number Shared
LPAR2_HUMAN Q9HBW0 CHEMBL3724 Lysophosphatidic Acid Receptor Edg-4, Human 27
LPAR3_HUMAN Q9UBY5 CHEMBL3250 Lysophosphatidic Acid Receptor Edg-7, Human 68
LPAR5_HUMAN Q9H1C0 CHEMBL5700 Lysophosphatidic Acid Receptor 5, Human 2
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
LPAR1_RAT P61794 CHEMBL4595 Lysophosphatidic Acid Receptor Edg-2, Rat 20 0 0 0
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
LPAR2_HUMAN Q9HBW0 CHEMBL3724 Lysophosphatidic Acid Receptor Edg-4, Human 59 3 0 0
LPAR3_HUMAN Q9UBY5 CHEMBL3250 Lysophosphatidic Acid Receptor Edg-7, Human 80 5 0 1
LPAR5_HUMAN Q9H1C0 CHEMBL5700 Lysophosphatidic Acid Receptor 5, Human 1 1 0 0

Clustered By Gene (0)

Clustered By Organism (1)

Code Description Substances Purchasable Natural In Man
LPAR1-1-E Lysophosphatidic Acid Receptor Edg-2 (cluster #1 Of 2), Eukaryotic 77 4 0 0
LPAR1-2-E Lysophosphatidic Acid Receptor Edg-2 (cluster #2 Of 2), Eukaryotic 7 1 0 0
Uniprot Swissprot Chembl Description Number Shared
LPAR3_HUMAN Q9UBY5 CHEMBL3250 Lysophosphatidic Acid Receptor Edg-7, Human 68
LPAR2_HUMAN Q9HBW0 CHEMBL3724 Lysophosphatidic Acid Receptor Edg-4, Human 27
LPAR1_RAT P61794 CHEMBL4595 Lysophosphatidic Acid Receptor Edg-2, Rat 22
Z80390 Z80390 CHEMBL390 PC-3 (Prostate Carcinoma Cells) 14
Z50587 Z50587 CHEMBL372 Homo Sapiens 5
ENPP2_HUMAN Q13822 CHEMBL3691 Autotaxin, Human 2
LPAR5_HUMAN Q9H1C0 CHEMBL5700 Lysophosphatidic Acid Receptor 5, Human 2