In ZINC since | Heavy atoms | Benign functionality |
---|---|---|
October 24th, 2009 | 35 | No |
Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
---|---|---|---|---|---|---|---|---|---|---|
Ref Reference (pH 7) | 5.77 | 16.47 | -58.08 | 1 | 6 | 1 | 60 | 481.636 | 12 | ↓ |
Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
---|---|---|---|---|---|
CXCR3-1-E | C-X-C Chemokine Receptor Type 3 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 375 | 0.26 | Binding ≤ 10μM |
Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
---|---|---|---|---|---|
CXCR3_HUMAN | P49682 | C-X-C Chemokine Receptor Type 3, Human | 375 | 0.26 | Binding ≤ 1μM |
CXCR3_HUMAN | P49682 | C-X-C Chemokine Receptor Type 3, Human | 375 | 0.26 | Binding ≤ 10μM |
Description | Species |
---|---|
Chemokine receptors bind chemokines | |
G alpha (i) signalling events |