Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	-4.19	0.54	-142.35	15	14	2	269	586.694	17	↓ MOL2 SDF SMILES Flexibase
Hi High (pH 8-9.5)	-4.19	-0.1	-68.92	13	14	0	266	584.678	17	↓ MOL2 SDF SMILES Flexibase
Mid Mid (pH 6-8)	-4.19	0.23	-78.05	14	14	1	267	585.686	17	↓ MOL2 SDF SMILES Flexibase

Clustered Target Annotations
Code	Description	Organism Class	Affinity (nM)	LE (kcal/mol/atom)	Type
OPRM-1-E	Mu-type Opioid Receptor (cluster #1 Of 4), Eukaryotic	Eukaryotes	6	0.27	Binding ≤ 10μM
Z50512-1-O	Cavia Porcellus (cluster #1 Of 7), Other	Other	257	0.22	Functional ≤ 10μM
Z50594-4-O	Mus Musculus (cluster #4 Of 9), Other	Other	659	0.21	Functional ≤ 10μM

ChEMBL Target Annotations
Uniprot	Swissprot	Description	Affinity (nM)	LE (kcal/mol/atom)	Type
OPRM_RAT	P33535	Mu Opioid Receptor, Rat	5.78	0.27	Binding ≤ 1μM
OPRM_RAT	P33535	Mu Opioid Receptor, Rat	5.78	0.27	Binding ≤ 10μM
Z50512	Z50512	Cavia Porcellus	257	0.22	Functional ≤ 10μM
Z50594	Z50594	Mus Musculus	659	0.21	Functional ≤ 10μM

Description	Species
G alpha (i) signalling events	Rattus norvegicus (OPRM_RAT)
G-protein activation	Rattus norvegicus (OPRM_RAT)
Opioid Signalling	Rattus norvegicus (OPRM_RAT)
Peptide ligand-binding receptors	Rattus norvegicus (OPRM_RAT)