Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.78	3.28	-282.45	11	7	3	134	495.688	15	↓ MOL2 SDF SMILES Flexibase
Hi High (pH 8-9.5)	2.78	1.26	-59.84	9	7	1	124	493.672	15	↓ MOL2 SDF SMILES Flexibase
Hi High (pH 8-9.5)	2.78	2.18	-137.29	10	7	2	129	494.68	15	↓ MOL2 SDF SMILES Flexibase
Mid Mid (pH 6-8)	2.78	3.27	-258.4	11	7	3	134	495.688	15	↓ MOL2 SDF SMILES Flexibase
Mid Mid (pH 6-8)	2.78	2.89	-123.16	10	7	2	132	494.68	15	↓ MOL2 SDF SMILES Flexibase
Mid Mid (pH 6-8)	2.78	1.76	-147.78	10	7	2	129	494.68	15	↓ MOL2 SDF SMILES Flexibase
Lo Low (pH 4.5-6)	2.78	4.37	-458.69	12	7	4	138	496.696	15	↓ MOL2 SDF SMILES Flexibase

Clustered Target Annotations
Code	Description	Organism Class	Affinity (nM)	LE (kcal/mol/atom)	Type
OPRM-1-E	Mu-type Opioid Receptor (cluster #1 Of 4), Eukaryotic	Eukaryotes	138	0.27	Binding ≤ 10μM

ChEMBL Target Annotations
Uniprot	Swissprot	Description	Affinity (nM)	LE (kcal/mol/atom)	Type
OPRM_RAT	P33535	Mu Opioid Receptor, Rat	138	0.27	Binding ≤ 1μM
OPRM_RAT	P33535	Mu Opioid Receptor, Rat	138	0.27	Binding ≤ 10μM

Description	Species
G alpha (i) signalling events	Rattus norvegicus (OPRM_RAT)
G-protein activation	Rattus norvegicus (OPRM_RAT)
Opioid Signalling	Rattus norvegicus (OPRM_RAT)
Peptide ligand-binding receptors	Rattus norvegicus (OPRM_RAT)