Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.26	6.14	-277.41	10	6	3	113	479.689	15	↓ MOL2 SDF SMILES Flexibase
Hi High (pH 8-9.5)	3.26	4.12	-56.23	8	6	1	104	477.673	15	↓ MOL2 SDF SMILES Flexibase
Hi High (pH 8-9.5)	3.26	5.03	-133.36	9	6	2	109	478.681	15	↓ MOL2 SDF SMILES Flexibase
Mid Mid (pH 6-8)	3.26	5.68	-113.7	9	6	2	112	478.681	15	↓ MOL2 SDF SMILES Flexibase
Mid Mid (pH 6-8)	3.26	6.12	-252.63	10	6	3	113	479.689	15	↓ MOL2 SDF SMILES Flexibase
Mid Mid (pH 6-8)	3.26	4.62	-143.22	9	6	2	109	478.681	15	↓ MOL2 SDF SMILES Flexibase
Lo Low (pH 4.5-6)	3.26	7.21	-451.91	11	6	4	118	480.697	15	↓ MOL2 SDF SMILES Flexibase

Clustered Target Annotations
Code	Description	Organism Class	Affinity (nM)	LE (kcal/mol/atom)	Type
OPRM-1-E	Mu-type Opioid Receptor (cluster #1 Of 4), Eukaryotic	Eukaryotes	47	0.29	Binding ≤ 10μM

ChEMBL Target Annotations
Uniprot	Swissprot	Description	Affinity (nM)	LE (kcal/mol/atom)	Type
OPRM_RAT	P33535	Mu Opioid Receptor, Rat	47	0.29	Binding ≤ 1μM
OPRM_RAT	P33535	Mu Opioid Receptor, Rat	47	0.29	Binding ≤ 10μM

Description	Species
G alpha (i) signalling events	Rattus norvegicus (OPRM_RAT)
G-protein activation	Rattus norvegicus (OPRM_RAT)
Opioid Signalling	Rattus norvegicus (OPRM_RAT)
Peptide ligand-binding receptors	Rattus norvegicus (OPRM_RAT)