Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	3.20	5.18	-209.82	11	8	3	137	578.822	17	↓ MOL2 SDF SMILES Flexibase
Hi High (pH 8-9.5)	3.20	4.06	-105.52	10	8	2	132	577.814	17	↓ MOL2 SDF SMILES Flexibase
Hi High (pH 8-9.5)	3.20	3.19	-53.53	9	8	1	128	576.806	17	↓ MOL2 SDF SMILES Flexibase
Hi High (pH 8-9.5)	3.20	3.93	-135.32	10	8	2	132	577.814	17	↓ MOL2 SDF SMILES Flexibase
Mid Mid (pH 6-8)	3.20	5.5	-200.38	11	8	3	133	578.822	17	↓ MOL2 SDF SMILES Flexibase
Mid Mid (pH 6-8)	3.20	6.48	-338.82	12	8	4	138	579.83	17	↓ MOL2 SDF SMILES Flexibase
Mid Mid (pH 6-8)	3.20	6.63	-357.16	12	8	4	138	579.83	17	↓ MOL2 SDF SMILES Flexibase

Clustered Target Annotations
Code	Description	Organism Class	Affinity (nM)	LE (kcal/mol/atom)	Type
OPRM-1-E	Mu-type Opioid Receptor (cluster #1 Of 4), Eukaryotic	Eukaryotes	13	0.26	Binding ≤ 10μM

ChEMBL Target Annotations
Uniprot	Swissprot	Description	Affinity (nM)	LE (kcal/mol/atom)	Type
OPRM_RAT	P33535	Mu Opioid Receptor, Rat	13	0.26	Binding ≤ 1μM
OPRM_RAT	P33535	Mu Opioid Receptor, Rat	13	0.26	Binding ≤ 10μM

Description	Species
G alpha (i) signalling events	Rattus norvegicus (OPRM_RAT)
G-protein activation	Rattus norvegicus (OPRM_RAT)
Opioid Signalling	Rattus norvegicus (OPRM_RAT)
Peptide ligand-binding receptors	Rattus norvegicus (OPRM_RAT)