Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Hi High (pH 8-9.5)	4.60	9.6	-145.33	5	6	2	68	520.762	15	↓ MOL2 SDF SMILES Flexibase
Hi High (pH 8-9.5)	4.60	8.39	-6.78	3	6	0	62	518.746	15	↓ MOL2 SDF SMILES Flexibase
Hi High (pH 8-9.5)	4.60	9.46	-55.76	4	6	1	67	519.754	15	↓ MOL2 SDF SMILES Flexibase
Mid Mid (pH 6-8)	4.60	12.1	-119.29	5	6	2	65	520.762	15	↓ MOL2 SDF SMILES Flexibase
Mid Mid (pH 6-8)	4.60	11.67	-214.49	6	6	3	69	521.77	15	↓ MOL2 SDF SMILES Flexibase
Mid Mid (pH 6-8)	4.60	10.45	-99.81	5	6	2	68	520.762	15	↓ MOL2 SDF SMILES Flexibase

Clustered Target Annotations
Code	Description	Organism Class	Affinity (nM)	LE (kcal/mol/atom)	Type
OPRM-1-E	Mu-type Opioid Receptor (cluster #1 Of 4), Eukaryotic	Eukaryotes	876	0.22	Binding ≤ 10μM

ChEMBL Target Annotations
Uniprot	Swissprot	Description	Affinity (nM)	LE (kcal/mol/atom)	Type
OPRM_RAT	P33535	Mu Opioid Receptor, Rat	876	0.22	Binding ≤ 1μM
OPRM_RAT	P33535	Mu Opioid Receptor, Rat	876	0.22	Binding ≤ 10μM

Description	Species
G alpha (i) signalling events	Rattus norvegicus (OPRM_RAT)
G-protein activation	Rattus norvegicus (OPRM_RAT)
Opioid Signalling	Rattus norvegicus (OPRM_RAT)
Peptide ligand-binding receptors	Rattus norvegicus (OPRM_RAT)