Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	1.64	2.5	-108.23	11	11	2	200	622.811	15	↓ MOL2 SDF SMILES Flexibase
Hi High (pH 8-9.5)	1.64	1.94	-27.35	9	11	0	196	620.795	15	↓ MOL2 SDF SMILES Flexibase
Mid Mid (pH 6-8)	1.64	2.18	-67.86	10	11	1	198	621.803	15	↓ MOL2 SDF SMILES Flexibase
Mid Mid (pH 6-8)	1.64	2.25	-60.91	10	11	1	198	621.803	15	↓ MOL2 SDF SMILES Flexibase

Clustered Target Annotations
Code	Description	Organism Class	Affinity (nM)	LE (kcal/mol/atom)	Type
OPRD-1-E	Delta Opioid Receptor (cluster #1 Of 3), Eukaryotic	Eukaryotes	19	0.24	Binding ≤ 10μM
OPRM-1-E	Mu-type Opioid Receptor (cluster #1 Of 4), Eukaryotic	Eukaryotes	0	0.00	Binding ≤ 10μM
OPRM-1-E	Mu Opioid Receptor (cluster #1 Of 2), Eukaryotic	Eukaryotes	5	0.26	Functional ≤ 10μM

ChEMBL Target Annotations
Uniprot	Swissprot	Description	Affinity (nM)	LE (kcal/mol/atom)	Type
OPRD_RAT	P33533	Delta Opioid Receptor, Rat	18.8	0.24	Binding ≤ 1μM
OPRM_RAT	P33535	Mu Opioid Receptor, Rat	0.1	0.31	Binding ≤ 1μM
OPRD_RAT	P33533	Delta Opioid Receptor, Rat	18.8	0.24	Binding ≤ 10μM
OPRM_RAT	P33535	Mu Opioid Receptor, Rat	0.1	0.31	Binding ≤ 10μM
OPRM_CAVPO	P97266	Mu Opioid Receptor, Guinea Pig	4.93	0.26	Functional ≤ 10μM

Description	Species
G alpha (i) signalling events	Rattus norvegicus (OPRD_RAT)
G-protein activation	Rattus norvegicus (OPRM_RAT)
Opioid Signalling	Rattus norvegicus (OPRM_RAT)
Peptide ligand-binding receptors	Rattus norvegicus (OPRD_RAT)