Physical Representations
Type
pH range
|
xlogP
|
Des A‑Pol
Apolar desolvation
(kcal/mol)
|
Des Pol
Polar desolvation
(kcal/mol)
|
H Don
H-bond donors
|
H Acc
H-bond acceptors
|
Chg
Net charge
|
tPSA
(Ų)
|
MWT
Molecular weight
(g/mol)
|
RB
Rotatable bonds
|
DL |
Ref
Reference (pH 7)
|
2.87 |
13.25 |
-44.23 |
2 |
9 |
1 |
106 |
546.673 |
10 |
↓
|
Mid
Mid (pH 6-8)
|
2.87 |
12.74 |
-24.09 |
1 |
9 |
0 |
105 |
545.665 |
10 |
↓
|
Clustered Target Annotations
Code |
Organism Class |
Affinity (nM) |
LE (kcal/mol/atom) |
Type |
FNTA-1-E |
Protein Farnesyltransferase/geranylgeranyltransferase Type I Alpha Subunit (cluster #1 Of 3), Eukaryotic |
Eukaryotes |
1 |
0.32 |
Binding ≤ 10μM
|
FNTB-1-E |
Protein Farnesyltransferase Beta Subunit (cluster #1 Of 3), Eukaryotic |
Eukaryotes |
1 |
0.32 |
Binding ≤ 10μM
|
Reactome Annotations from Targets (via Uniprot)
Description |
Species |
Apoptotic cleavage of cellular proteins |
|
Inactivation, recovery and regulation of the phototransduction cascade |
|
No pre-computed analogs available. Try a structural similarity search.