Physical Representations
Type
pH range
|
xlogP
|
Des A‑Pol
Apolar desolvation
(kcal/mol)
|
Des Pol
Polar desolvation
(kcal/mol)
|
H Don
H-bond donors
|
H Acc
H-bond acceptors
|
Chg
Net charge
|
tPSA
(Ų)
|
MWT
Molecular weight
(g/mol)
|
RB
Rotatable bonds
|
DL |
Ref
Reference (pH 7)
|
3.16 |
14.15 |
-47.64 |
3 |
10 |
1 |
126 |
552.677 |
13 |
↓
|
Mid
Mid (pH 6-8)
|
3.16 |
13.68 |
-23.2 |
2 |
10 |
0 |
125 |
551.669 |
13 |
↓
|
Clustered Target Annotations
Code |
Organism Class |
Affinity (nM) |
LE (kcal/mol/atom) |
Type |
FNTA-1-E |
Protein Farnesyltransferase/geranylgeranyltransferase Type I Alpha Subunit (cluster #1 Of 3), Eukaryotic |
Eukaryotes |
500 |
0.23 |
Binding ≤ 10μM
|
FNTB-1-E |
Protein Farnesyltransferase Beta Subunit (cluster #1 Of 3), Eukaryotic |
Eukaryotes |
500 |
0.23 |
Binding ≤ 10μM
|
Reactome Annotations from Targets (via Uniprot)
Description |
Species |
Apoptotic cleavage of cellular proteins |
|
Inactivation, recovery and regulation of the phototransduction cascade |
|
No pre-computed analogs available. Try a structural similarity search.