| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| October 26th, 2009 | 17 | Yes |
Popular Name: DNC006461 DNC006461
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 1.87 | 4.88 | -7.1 | 3 | 3 | 0 | 55 | 223.279 | 1 | ↓ |
| Lo Low (pH 4.5-6) | 1.87 | 5.36 | -35.44 | 4 | 3 | 1 | 56 | 224.287 | 1 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| IMDH2-2-E | Inosine-5'-monophosphate Dehydrogenase 2 (cluster #2 Of 2), Eukaryotic | Eukaryotes | 419 | 0.53 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| IMDH2_HUMAN | P12268 | Inosine-5'-monophosphate Dehydrogenase 2, Human | 419 | 0.53 | Binding ≤ 1μM |
| IMDH2_HUMAN | P12268 | Inosine-5'-monophosphate Dehydrogenase 2, Human | 419 | 0.53 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Purine ribonucleoside monophosphate biosynthesis |
