| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| October 26th, 2009 | 28 | No |
Popular Name: [4-(4-fluorophenyl)-5-heptyl-2,6-diisopropyl-3-pyridyl]methanol [4-(4-fluorophenyl)-5-heptyl-2,6…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 8.16 | 12.48 | -5.18 | 1 | 2 | 0 | 33 | 385.567 | 10 | ↓ |
| Mid Mid (pH 6-8) | 8.16 | 12.84 | -26 | 2 | 2 | 1 | 34 | 386.575 | 10 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| GLR-2-E | Glucagon Receptor (cluster #2 Of 2), Eukaryotic | Eukaryotes | 700 | 0.31 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| GLR_HUMAN | P47871 | Glucagon Receptor, Human | 700 | 0.31 | Binding ≤ 1μM |
| GLR_HUMAN | P47871 | Glucagon Receptor, Human | 700 | 0.31 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| G alpha (q) signalling events | |
| G alpha (s) signalling events | |
| Glucagon signaling in metabolic regulation | |
| Glucagon-type ligand receptors |
