| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| September 27th, 2005 | 32 | Yes |
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 0.99 | -8.8 | -57.03 | 9 | 10 | 1 | 176 | 441.512 | 9 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| TRYB1-1-E | Tryptase Beta-1 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 330 | 0.28 | Binding ≤ 10μM |
| TRYB1-1-E | Tryptase Beta-1 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 840 | 0.27 | Binding ≤ 10μM |
| TRYD-1-E | Tryptase Delta (cluster #1 Of 1), Eukaryotic | Eukaryotes | 840 | 0.27 | Binding ≤ 10μM |
| TRYG1-1-E | Tryptase Gamma (cluster #1 Of 1), Eukaryotic | Eukaryotes | 840 | 0.27 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| TRYB1_HUMAN | Q15661 | Tryptase Beta-1, Human | 330 | 0.28 | Binding ≤ 1μM |
| TRYD_HUMAN | Q9BZJ3 | Tryptase Delta, Human | 840 | 0.27 | Binding ≤ 1μM |
| TRYG1_HUMAN | Q9NRR2 | Tryptase Gamma, Human | 840 | 0.27 | Binding ≤ 1μM |
| TRYB1_HUMAN | Q15661 | Tryptase Beta-1, Human | 330 | 0.28 | Binding ≤ 10μM |
| TRYD_HUMAN | Q9BZJ3 | Tryptase Delta, Human | 840 | 0.27 | Binding ≤ 10μM |
| TRYG1_HUMAN | Q9NRR2 | Tryptase Gamma, Human | 840 | 0.27 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Activation of Matrix Metalloproteinases |
No pre-computed analogs available. Try a structural similarity search.