Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	-1.26	9.09	-86.61	4	9	0	131	442.545	12	↓ MOL2 SDF SMILES Flexibase
Hi High (pH 8-9.5)	-1.26	9.62	-79.43	4	9	0	131	442.545	12	↓ MOL2 SDF SMILES Flexibase
Mid Mid (pH 6-8)	-1.26	9.55	-63.45	3	9	-1	130	441.537	12	↓ MOL2 SDF SMILES Flexibase
Mid Mid (pH 6-8)	-1.26	8.53	-60.64	3	9	-1	130	441.537	12	↓ MOL2 SDF SMILES Flexibase
Mid Mid (pH 6-8)	-1.26	9.64	-79.89	4	9	0	131	442.545	12	↓ MOL2 SDF SMILES Flexibase
Mid Mid (pH 6-8)	-1.26	9.06	-60.66	3	9	-1	130	441.537	12	↓ MOL2 SDF SMILES Flexibase
Lo Low (pH 4.5-6)	-1.26	9.63	-127.19	5	9	1	132	443.553	12	↓ MOL2 SDF SMILES Flexibase
Lo Low (pH 4.5-6)	-1.26	9.72	-122.8	5	9	1	132	443.553	12	↓ MOL2 SDF SMILES Flexibase

Note Type	Comments	Provided By
PUBCHEM_PATENT_ID	EP0817630A1; US5534537; US5578629; WO1996030015A1	IBM Patent Data

Clustered Target Annotations
Code	Description	Organism Class	Affinity (nM)	LE (kcal/mol/atom)	Type
FNTA-1-E	Protein Farnesyltransferase/geranylgeranyltransferase Type I Alpha Subunit (cluster #1 Of 2), Eukaryotic	Eukaryotes	870	0.27	Functional ≤ 10μM
FNTB-1-E	Protein Farnesyltransferase Beta Subunit (cluster #1 Of 2), Eukaryotic	Eukaryotes	870	0.27	Functional ≤ 10μM

ChEMBL Target Annotations
Uniprot	Swissprot	Description	Affinity (nM)	LE (kcal/mol/atom)	Type
FNTB_HUMAN	P49356	Protein Farnesyltransferase Beta Subunit, Human	870	0.27	Functional ≤ 10μM
FNTA_HUMAN	P49354	Protein Farnesyltransferase/geranylgeranyltransferase Type I Alpha Subunit, Human	870	0.27	Functional ≤ 10μM

Description	Species
Apoptotic cleavage of cellular proteins	Homo sapiens (FNTA_HUMAN)
Inactivation, recovery and regulation of the phototransduction cascade	Homo sapiens (FNTA_HUMAN)