In ZINC since | Heavy atoms | Benign functionality |
---|---|---|
January 4th, 2010 | 33 | No |
Popular Name: 4-heptoxy-N-[4-oxo-2-(2H-tetrazol-5-yl)chromen-8-yl]benzamide 4-heptoxy-N-[4-oxo-2-(2H-tetrazo…
None
Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
---|---|---|---|---|---|---|---|---|---|---|
Ref Reference (pH 7) | 5.68 | 7.56 | -34.71 | 3 | 9 | 1 | 125 | 448.503 | 9 | ↓ |
Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
---|---|---|---|---|---|
CLTR1-1-E | Cysteinyl Leukotriene Receptor 1 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 1 | 0.38 | Functional ≤ 10μM |
CLTR2-1-E | Cysteinyl Leukotriene Receptor 2 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 1 | 0.38 | Functional ≤ 10μM |
Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
---|---|---|---|---|---|
CLTR1_HUMAN | Q9Y271 | Cysteinyl Leukotriene Receptor 1, Human | 0.5 | 0.39 | Functional ≤ 10μM |
CLTR2_HUMAN | Q9NS75 | Cysteinyl Leukotriene Receptor 2, Human | 0.5 | 0.39 | Functional ≤ 10μM |
Description | Species |
---|---|
G alpha (q) signalling events | |
Leukotriene receptors |