| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| January 5th, 2010 | 24 | No |
Popular Name: 1-[(2S)-2-(3,4-dimethylphenyl)thiazolidin-3-yl]-2-(4-methoxyphenyl)ethanone 1-[(2S)-2-(3,4-dimethylphenyl)th…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 4.31 | 11.21 | -14.11 | 0 | 3 | 0 | 30 | 341.476 | 4 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| KCNA5-1-E | Voltage-gated Potassium Channel Subunit Kv1.5 (cluster #1 Of 3), Eukaryotic | Eukaryotes | 537 | 0.37 | Binding ≤ 10μM |
| KCNA5-1-E | Voltage-gated Potassium Channel Subunit Kv1.5 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 537 | 0.37 | Functional ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| KCNA5_HUMAN | P22460 | Voltage-gated Potassium Channel Subunit Kv1.5, Human | 537 | 0.37 | Binding ≤ 1μM |
| KCNA5_HUMAN | P22460 | Voltage-gated Potassium Channel Subunit Kv1.5, Human | 537 | 0.37 | Binding ≤ 10μM |
| KCNA5_HUMAN | P22460 | Voltage-gated Potassium Channel Subunit Kv1.5, Human | 537 | 0.37 | Functional ≤ 10μM |
| Description | Species |
|---|---|
| Voltage gated Potassium channels |
