| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| January 5th, 2010 | 31 | No |
Popular Name: 1-[4-[2-(1-methyl-4-piperidyl)ethyl]-1-piperidyl]pentadecan-1-one 1-[4-[2-(1-methyl-4-piperidyl)et…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 8.76 | 18.89 | -38.69 | 1 | 3 | 1 | 25 | 435.761 | 16 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| GNAI3-1-E | Guanine Nucleotide-binding Protein G(k), Alpha-3 Subunit (cluster #1 Of 1), Eukaryotic | Eukaryotes | 6100 | 0.24 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| GNAI3_HUMAN | P08754 | Guanine Nucleotide-binding Protein G(k), Alpha-3 Subunit, Human | 6100 | 0.24 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Adenylate cyclase inhibitory pathway | |
| ADP signalling through P2Y purinoceptor 12 | |
| G alpha (i) signalling events | |
| G alpha (s) signalling events | |
| G alpha (z) signalling events | |
| G-protein activation | |
| PLC beta mediated events |
