| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| September 30th, 2005 | 25 | Yes |
Popular Name: 15(R)-Prostaglandin E2 15(R)-Prostaglandin E2
Find On: PubMed — Wikipedia — Google
CAS Numbers: 363-24-6 , 38873-82-4
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 2.87 | -2.44 | -51.24 | 2 | 5 | -1 | 97 | 351.463 | 12 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| PE2R1-2-E | Prostanoid EP1 Receptor (cluster #2 Of 2), Eukaryotic | Eukaryotes | 18 | 0.43 | Binding ≤ 10μM |
| PE2R2-2-E | Prostanoid EP2 Receptor (cluster #2 Of 2), Eukaryotic | Eukaryotes | 38 | 0.42 | Binding ≤ 10μM |
| PE2R3-2-E | Prostanoid EP3 Receptor (cluster #2 Of 3), Eukaryotic | Eukaryotes | 5 | 0.46 | Binding ≤ 10μM |
| PE2R4-2-E | Prostanoid EP4 Receptor (cluster #2 Of 2), Eukaryotic | Eukaryotes | 3 | 0.48 | Binding ≤ 10μM |
| PE2R2-1-E | Prostanoid EP2 Receptor (cluster #1 Of 1), Eukaryotic | Eukaryotes | 2 | 0.49 | Functional ≤ 10μM |
| PI2R-1-E | Prostanoid IP Receptor (cluster #1 Of 1), Eukaryotic | Eukaryotes | 260 | 0.37 | Functional ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| PE2R1_MOUSE | P35375 | Prostanoid EP1 Receptor, Mouse | 18 | 0.43 | Binding ≤ 1μM |
| PE2R2_MOUSE | Q62053 | Prostanoid EP2 Receptor, Mouse | 38 | 0.42 | Binding ≤ 1μM |
| PE2R3_MOUSE | P30557 | Prostanoid EP3 Receptor, Mouse | 5 | 0.46 | Binding ≤ 1μM |
| PE2R4_MOUSE | P32240 | Prostanoid EP4 Receptor, Mouse | 3.1 | 0.48 | Binding ≤ 1μM |
| PE2R1_MOUSE | P35375 | Prostanoid EP1 Receptor, Mouse | 18 | 0.43 | Binding ≤ 10μM |
| PE2R2_MOUSE | Q62053 | Prostanoid EP2 Receptor, Mouse | 38 | 0.42 | Binding ≤ 10μM |
| PE2R3_MOUSE | P30557 | Prostanoid EP3 Receptor, Mouse | 5 | 0.46 | Binding ≤ 10μM |
| PE2R4_MOUSE | P32240 | Prostanoid EP4 Receptor, Mouse | 3.1 | 0.48 | Binding ≤ 10μM |
| PE2R2_MOUSE | Q62053 | Prostanoid EP2 Receptor, Mouse | 2.1 | 0.49 | Functional ≤ 10μM |
| PI2R_HUMAN | P43119 | Prostanoid IP Receptor, Human | 260 | 0.37 | Functional ≤ 10μM |
| Description | Species |
|---|---|
| G alpha (q) signalling events | |
| G alpha (s) signalling events | |
| Prostacyclin signalling through prostacyclin receptor | |
| Prostanoid ligand receptors |
