| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| October 3rd, 2005 | 13 | Yes |
Popular Name: 2-(1-Adamantyl)ethanamine 2-(1-Adamantyl)ethanamine
Find On: PubMed — Wikipedia — Google
CAS Numbers: 24644-08-4 , 26482-53-1
2-(1-Adamantyl)ethanamine hydrochloride
2-(adamantan-1-yl)ethan-1-amine
ADAMANTYLETHANAMINEHYDROCHLORID
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 2.33 | -2.22 | -44.3 | 3 | 1 | 1 | 27 | 180.315 | 2 | ↓ |
| Note Type | Comments | Provided By |
|---|---|---|
| MP | 240 - 242 | Enamine Building Blocks |
| MP | 240...242 | Enamine Building Blocks |
| MP | 329 - 331 | Enamine Building Blocks |
| MP | 329...331 | Enamine Building Blocks |
| MP | 394 - 396 | Enamine Building Blocks |
| purity | 9.500000000000000e+001 | Enamine Building Blocks Enamine Building Blocks |
| Purity | 95% | Fluorochem |
| Warnings | IRRITANT | Matrix Scientific |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| NMD3A-1-E | Glutamate [NMDA] Receptor Subunit 3A (cluster #1 Of 6), Eukaryotic | Eukaryotes | 3800 | 0.58 | Binding ≤ 10μM |
| NMD3B-1-E | Glutamate [NMDA] Receptor Subunit 3B (cluster #1 Of 6), Eukaryotic | Eukaryotes | 3800 | 0.58 | Binding ≤ 10μM |
| NMDE1-2-E | Glutamate [NMDA] Receptor Subunit Epsilon 1 (cluster #2 Of 5), Eukaryotic | Eukaryotes | 3800 | 0.58 | Binding ≤ 10μM |
| NMDE2-2-E | Glutamate [NMDA] Receptor Subunit Epsilon 2 (cluster #2 Of 5), Eukaryotic | Eukaryotes | 3800 | 0.58 | Binding ≤ 10μM |
| NMDE3-4-E | Glutamate [NMDA] Receptor Subunit Epsilon 3 (cluster #4 Of 4), Eukaryotic | Eukaryotes | 3800 | 0.58 | Binding ≤ 10μM |
| NMDE4-1-E | Glutamate [NMDA] Receptor Subunit Epsilon 4 (cluster #1 Of 6), Eukaryotic | Eukaryotes | 3800 | 0.58 | Binding ≤ 10μM |
| NMDZ1-5-E | Glutamate (NMDA) Receptor Subunit Zeta 1 (cluster #5 Of 6), Eukaryotic | Eukaryotes | 3800 | 0.58 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| NMDZ1_HUMAN | Q05586 | Glutamate (NMDA) Receptor Subunit Zeta 1, Human | 3800 | 0.58 | Binding ≤ 10μM |
| NMD3A_HUMAN | Q8TCU5 | Glutamate [NMDA] Receptor Subunit 3A, Human | 3800 | 0.58 | Binding ≤ 10μM |
| NMD3B_HUMAN | O60391 | Glutamate [NMDA] Receptor Subunit 3B, Human | 3800 | 0.58 | Binding ≤ 10μM |
| NMDE1_HUMAN | Q12879 | Glutamate [NMDA] Receptor Subunit Epsilon 1, Human | 3800 | 0.58 | Binding ≤ 10μM |
| NMDE2_HUMAN | Q13224 | Glutamate [NMDA] Receptor Subunit Epsilon 2, Human | 3800 | 0.58 | Binding ≤ 10μM |
| NMDE3_HUMAN | Q14957 | Glutamate [NMDA] Receptor Subunit Epsilon 3, Human | 3800 | 0.58 | Binding ≤ 10μM |
| NMDE4_HUMAN | O15399 | Glutamate [NMDA] Receptor Subunit Epsilon 4, Human | 3800 | 0.58 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| CREB phosphorylation through the activation of CaMKII | |
| EPHB-mediated forward signaling | |
| Ras activation uopn Ca2+ infux through NMDA receptor | |
| Unblocking of NMDA receptor, glutamate binding and activation |
No pre-computed analogs available. Try a structural similarity search.