| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| October 6th, 2005 | 22 | Yes |
Popular Name: 2-{[(4-bromophenyl)sulfonyl]amino}-3-phenylpropanoic acid 2-{[(4-bromophenyl)sulfonyl]amin…
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CAS Numbers: 37642-61-8 , [37642-61-8]
2-([(4-bromophenyl)sulfonyl]amino)-3-phenylpropanoic acid
2-{[(4-bromophenyl)sulfonyl]amino}-3-phenylpropanoicacid
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 1.40 | 6.63 | -51.17 | 1 | 5 | -1 | 86 | 383.243 | 6 | ↓ |
| Note Type | Comments | Provided By |
|---|---|---|
| melting_point | 165 - 167 | KeyOrganics |
| MP | 165-167° | Matrix Scientific |
| Purity | >95% | Matrix Scientific |
| Warnings | IRRITANT | Matrix Scientific |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| MMP2-1-E | 72 KDa Type IV Collagenase (cluster #1 Of 3), Eukaryotic | Eukaryotes | 7100 | 0.33 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| MMP2_HUMAN | P08253 | Matrix Metalloproteinase-2, Human | 7100 | 0.33 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Activation of Matrix Metalloproteinases | |
| Collagen degradation | |
| Degradation of the extracellular matrix | |
| EPH-ephrin mediated repulsion of cells | |
| Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-l |
