| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| October 20th, 2005 | 45 | No |
Popular Name: tert-butyl tert-butyl
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 3.06 | 9.24 | -66.95 | 6 | 11 | 1 | 165 | 640.827 | 15 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| SSR2-1-E | Somatostatin Receptor 2 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 3 | 0.27 | Binding ≤ 10μM |
| SSR2-1-E | Somatostatin Receptor 2 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 120 | 0.22 | Functional ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| SSR2_HUMAN | P30874 | Somatostatin Receptor 2, Human | 3.2 | 0.26 | Binding ≤ 1μM |
| SSR2_HUMAN | P30874 | Somatostatin Receptor 2, Human | 3.2 | 0.26 | Binding ≤ 10μM |
| SSR2_HUMAN | P30874 | Somatostatin Receptor 2, Human | 120 | 0.22 | Functional ≤ 10μM |
| Description | Species |
|---|---|
| G alpha (i) signalling events | |
| Peptide ligand-binding receptors |
