| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| October 20th, 2005 | 40 | No |
Popular Name: 5-[(3,4,5-tribenzyloxy-6-methoxy-tetrahydropyran-2-yl)methoxy]pentan-1-amine 5-[(3,4,5-tribenzyloxy-6-methoxy…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 4.64 | -3.53 | -47.67 | 3 | 7 | 1 | 83 | 550.716 | 17 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| SSR1-1-E | Somatostatin Receptor 1 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 5900 | 0.18 | Binding ≤ 10μM |
| SSR2-1-E | Somatostatin Receptor 2 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 5900 | 0.18 | Binding ≤ 10μM |
| SSR3-1-E | Somatostatin Receptor 3 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 3000 | 0.19 | Binding ≤ 10μM |
| SSR4-1-E | Somatostatin Receptor 4 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 5900 | 0.18 | Binding ≤ 10μM |
| SSR5-1-E | Somatostatin Receptor 5 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 3000 | 0.19 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| SSR1_MOUSE | P30873 | Somatostatin Receptor 1, Mouse | 5900 | 0.18 | Binding ≤ 10μM |
| SSR1_HUMAN | P30872 | Somatostatin Receptor 1, Human | 2400 | 0.20 | Binding ≤ 10μM |
| SSR2_MOUSE | P30875 | Somatostatin Receptor 2, Mouse | 5900 | 0.18 | Binding ≤ 10μM |
| SSR2_HUMAN | P30874 | Somatostatin Receptor 2, Human | 4600 | 0.19 | Binding ≤ 10μM |
| SSR3_HUMAN | P32745 | Somatostatin Receptor 3, Human | 3000 | 0.19 | Binding ≤ 10μM |
| SSR3_MOUSE | P30935 | Somatostatin Receptor 3, Mouse | 5900 | 0.18 | Binding ≤ 10μM |
| SSR4_MOUSE | P49660 | Somatostatin Receptor 4, Mouse | 5900 | 0.18 | Binding ≤ 10μM |
| SSR4_HUMAN | P31391 | Somatostatin Receptor 4, Human | 2000 | 0.20 | Binding ≤ 10μM |
| SSR5_MOUSE | O08858 | Somatostatin Receptor 5, Mouse | 5900 | 0.18 | Binding ≤ 10μM |
| SSR5_HUMAN | P35346 | Somatostatin Receptor 5, Human | 3000 | 0.19 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| G alpha (i) signalling events | |
| Peptide ligand-binding receptors |
