| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| October 21st, 2005 | 21 | Yes |
Popular Name: 4-[5-(2,5-dimethylphenyl)-1-methyl-pyrazol-3-yl]phenol 4-[5-(2,5-dimethylphenyl)-1-meth…
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| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 4.08 | 0.28 | -8.3 | 1 | 3 | 0 | 38 | 278.355 | 2 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| ERR1-1-E | Estrogen-related Receptor Alpha (cluster #1 Of 1), Eukaryotic | Eukaryotes | 1000 | 0.40 | Functional ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| ERR1_HUMAN | P11474 | Estrogen-related Receptor Alpha, Human | 1000 | 0.40 | Functional ≤ 10μM |
| Description | Species |
|---|---|
| Nuclear Receptor transcription pathway | |
| PPARA activates gene expression | |
| Transcriptional activation of mitochondrial biogenesis |
