| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| October 24th, 2005 | 25 | Yes |
Popular Name: OL-135 OL-135
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 4.87 | 0.21 | -9.29 | 0 | 4 | 0 | 55 | 334.419 | 9 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| EST1-6-E | Carboxylesterase (cluster #6 Of 7), Eukaryotic | Eukaryotes | 600 | 0.35 | Binding ≤ 10μM |
| FAAH1-5-E | Anandamide Amidohydrolase (cluster #5 Of 7), Eukaryotic | Eukaryotes | 5 | 0.46 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| EST1_HUMAN | P23141 | Acyl Coenzyme A:cholesterol Acyltransferase, Human | 600 | 0.35 | Binding ≤ 1μM |
| FAAH1_RAT | P97612 | Anandamide Amidohydrolase, Rat | 112 | 0.39 | Binding ≤ 1μM |
| FAAH1_MOUSE | O08914 | Anandamide Amidohydrolase, Mouse | 4.7 | 0.47 | Binding ≤ 1μM |
| FAAH1_HUMAN | O00519 | Anandamide Amidohydrolase, Human | 10 | 0.45 | Binding ≤ 1μM |
| EST1_HUMAN | P23141 | Acyl Coenzyme A:cholesterol Acyltransferase, Human | 600 | 0.35 | Binding ≤ 10μM |
| FAAH1_HUMAN | O00519 | Anandamide Amidohydrolase, Human | 10 | 0.45 | Binding ≤ 10μM |
| FAAH1_RAT | P97612 | Anandamide Amidohydrolase, Rat | 112 | 0.39 | Binding ≤ 10μM |
| FAAH1_MOUSE | O08914 | Anandamide Amidohydrolase, Mouse | 4.7 | 0.47 | Binding ≤ 10μM |
