| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| October 29th, 2005 | 30 | Yes |
Popular Name: [H]/N=C(\N)/N1CCc2ccc(cc2C1)OCC3(CCN(CC3)c4ccncc4)C(=O)O [H]/N=C(\N)/N1CCc2ccc(cc2C1)OCC3…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 1.00 | -4.37 | -84.32 | 5 | 8 | 1 | 121 | 410.498 | 6 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| FA10-1-E | Coagulation Factor X (cluster #1 Of 2), Eukaryotic | Eukaryotes | 30 | 0.35 | Binding ≤ 10μM |
| O77669-1-E | Coagulation Factor X (cluster #1 Of 1), Eukaryotic | Eukaryotes | 30 | 0.35 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| FA10_HUMAN | P00742 | Coagulation Factor X, Human | 19 | 0.36 | Binding ≤ 1μM |
| O77669_CANFA | O77669 | Coagulation Factor X, Canine | 19 | 0.36 | Binding ≤ 1μM |
| FA10_HUMAN | P00742 | Coagulation Factor X, Human | 19 | 0.36 | Binding ≤ 10μM |
| O77669_CANFA | O77669 | Coagulation Factor X, Canine | 19 | 0.36 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Common Pathway | |
| Extrinsic Pathway | |
| Gamma-carboxylation of protein precursors | |
| Intrinsic Pathway | |
| Removal of aminoterminal propeptides from gamma-carboxylated proteins | |
| Transport of gamma-carboxylated protein precursors from the endoplasmic reticulu |
No pre-computed analogs available. Try a structural similarity search.