| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| October 29th, 2005 | 31 | No |
Popular Name: C[N+]1(CCC(CC1)(c2ccc(cc2)Cl)O)CCCC(c3ccccc3)c4ccccc4 C[N+]1(CCC(CC1)(c2ccc(cc2)Cl)O)C…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 2.20 | 2.3 | -39.73 | 1 | 2 | 1 | 20 | 435.031 | 7 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| CCR1-1-E | C-C Chemokine Receptor Type 1 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 6 | 0.37 | Binding ≤ 10μM |
| CCR1-1-E | C-C Chemokine Receptor Type 1 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 1800 | 0.26 | Functional ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| CCR1_HUMAN | P32246 | C-C Chemokine Receptor Type 1, Human | 6 | 0.37 | Binding ≤ 1μM |
| CCR1_HUMAN | P32246 | C-C Chemokine Receptor Type 1, Human | 6 | 0.37 | Binding ≤ 10μM |
| CCR1_HUMAN | P32246 | C-C Chemokine Receptor Type 1, Human | 1800 | 0.26 | Functional ≤ 10μM |
| Description | Species |
|---|---|
| Chemokine receptors bind chemokines | |
| G alpha (i) signalling events |
