| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| October 29th, 2005 | 35 | No |
Popular Name: Cc1ccccc1c2cc(ccc2C(=O)N[C@@H](CCSC)C(=O)O)CN(C)CCC3CCCCC3 Cc1ccccc1c2cc(ccc2C(=O)N[C@@H](C…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 4.37 | 1.35 | -87.24 | 2 | 5 | 0 | 73 | 496.717 | 12 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| FNTA-1-E | Protein Farnesyltransferase/geranylgeranyltransferase Type I Alpha Subunit (cluster #1 Of 3), Eukaryotic | Eukaryotes | 1 | 0.36 | Binding ≤ 10μM |
| FNTB-1-E | Protein Farnesyltransferase Beta Subunit (cluster #1 Of 3), Eukaryotic | Eukaryotes | 1 | 0.36 | Binding ≤ 10μM |
| Z50597-1-O | Rattus Norvegicus (cluster #1 Of 12), Other | Other | 12 | 0.32 | Functional ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| FNTB_RAT | Q02293 | Protein Farnesyltransferase Beta Subunit, Rat | 0.87 | 0.36 | Binding ≤ 1μM |
| FNTA_RAT | Q04631 | Protein Farnesyltransferase/geranylgeranyltransferase Type I Alpha Subunit, Rat | 0.87 | 0.36 | Binding ≤ 1μM |
| FNTB_RAT | Q02293 | Protein Farnesyltransferase Beta Subunit, Rat | 0.87 | 0.36 | Binding ≤ 10μM |
| FNTA_RAT | Q04631 | Protein Farnesyltransferase/geranylgeranyltransferase Type I Alpha Subunit, Rat | 0.87 | 0.36 | Binding ≤ 10μM |
| Z50597 | Z50597 | Rattus Norvegicus | 12 | 0.32 | Functional ≤ 10μM |
| Description | Species |
|---|---|
| Inactivation, recovery and regulation of the phototransduction cascade |
