| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| October 31st, 2005 | 15 | Yes |
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | -0.13 | 3.75 | -97.44 | 2 | 5 | -1 | 97 | 214.241 | 4 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| GRIK1-3-E | Glutamate Receptor Ionotropic Kainate 1 (cluster #3 Of 3), Eukaryotic | Eukaryotes | 8180 | 0.47 | Binding ≤ 10μM |
| GRIK3-2-E | Glutamate Receptor Ionotropic Kainate 3 (cluster #2 Of 3), Eukaryotic | Eukaryotes | 376 | 0.60 | Binding ≤ 10μM |
| Z50597-3-O | Rattus Norvegicus (cluster #3 Of 5), Other | Other | 646 | 0.58 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| GRIK3_RAT | P42264 | Glutamate Receptor Ionotropic Kainate 3, Rat | 363.078055 | 0.60 | Binding ≤ 1μM |
| Z50597 | Z50597 | Rattus Norvegicus | 645.6 | 0.58 | Binding ≤ 1μM |
| GRIK1_RAT | P22756 | Glutamate Receptor Ionotropic Kainate 1, Rat | 8128.30516 | 0.48 | Binding ≤ 10μM |
| GRIK3_RAT | P42264 | Glutamate Receptor Ionotropic Kainate 3, Rat | 363.078055 | 0.60 | Binding ≤ 10μM |
| Z50597 | Z50597 | Rattus Norvegicus | 645.6 | 0.58 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Activation of Ca-permeable Kainate Receptor | |
| Activation of Na-permeable Kainate Receptors |
