In ZINC since | Heavy atoms | Benign functionality |
---|---|---|
April 6th, 2010 | 24 | Yes |
Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
---|---|---|---|---|---|---|---|---|---|---|
Ref Reference (pH 7) | 2.68 | 4.96 | -42.71 | 5 | 5 | 1 | 98 | 346.476 | 7 | ↓ |
Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
---|---|---|---|---|---|
FA10-2-E | Coagulation Factor X (cluster #2 Of 2), Eukaryotic | Eukaryotes | 2100 | 0.33 | Binding ≤ 10μM |
Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
---|---|---|---|---|---|
FA10_HUMAN | P00742 | Coagulation Factor X, Human | 2100 | 0.33 | Binding ≤ 10μM |
Description | Species |
---|---|
Common Pathway | |
Extrinsic Pathway | |
Gamma-carboxylation of protein precursors | |
Intrinsic Pathway | |
Removal of aminoterminal propeptides from gamma-carboxylated proteins | |
Transport of gamma-carboxylated protein precursors from the endoplasmic reticulu |