| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| April 6th, 2010 | 33 | Yes |
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 3.42 | 9.86 | -50.12 | 3 | 6 | 1 | 75 | 457.476 | 6 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| FA10-1-E | Coagulation Factor X (cluster #1 Of 2), Eukaryotic | Eukaryotes | 1 | 0.38 | Binding ≤ 10μM |
| Z102222-1-O | Plasma (cluster #1 Of 1), Other | Other | 4 | 0.36 | Functional ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| FA10_HUMAN | P00742 | Coagulation Factor X, Human | 0.57 | 0.39 | Binding ≤ 1μM |
| FA10_HUMAN | P00742 | Coagulation Factor X, Human | 0.57 | 0.39 | Binding ≤ 10μM |
| Z102222 | Z102222 | Plasma | 4.4 | 0.35 | Functional ≤ 10μM |
| Description | Species |
|---|---|
| Common Pathway | |
| Extrinsic Pathway | |
| Gamma-carboxylation of protein precursors | |
| Intrinsic Pathway | |
| Removal of aminoterminal propeptides from gamma-carboxylated proteins | |
| Transport of gamma-carboxylated protein precursors from the endoplasmic reticulu |
