| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| April 7th, 2010 | 32 | No |
Popular Name: (1R)-4-[3-(4-phenoxyphenoxy)phenyl]-1-phosphono-butane-1-sulfonic (1R)-4-[3-(4-phenoxyphenoxy)phen…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 2.19 | 6.81 | -114.22 | 1 | 8 | -2 | 136 | 476.443 | 10 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| FDFT-1-E | Squalene Synthetase (cluster #1 Of 4), Eukaryotic | Eukaryotes | 1100 | 0.26 | Binding ≤ 10μM |
| Z50185-2-O | Staphylococcus Aureus (cluster #2 Of 4), Other | Other | 100 | 0.31 | Functional ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| FDFT_HUMAN | P37268 | Squalene Synthetase, Human | 1100 | 0.26 | Binding ≤ 10μM |
| Z50185 | Z50185 | Staphylococcus Aureus | 100 | 0.31 | Functional ≤ 10μM |
| Description | Species |
|---|---|
| Activation of gene expression by SREBF (SREBP) | |
| Cholesterol biosynthesis | |
| PPARA activates gene expression |
