| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| April 13th, 2010 | 28 | Yes |
Popular Name: 4-chloro-N-[2-[[(S)-(4-chlorophenyl)-phenyl-methyl]amino]-2-oxo-ethyl]benzamide 4-chloro-N-[2-[[(S)-(4-chlorophe…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 5.27 | 10.2 | -10.14 | 2 | 4 | 0 | 58 | 413.304 | 6 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| SC6A5-2-E | Glycine Transporter 2 (cluster #2 Of 2), Eukaryotic | Eukaryotes | 5900 | 0.26 | Binding ≤ 10μM |
| SC6A9-1-E | Glycine Transporter 1 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 300 | 0.33 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| SC6A9_HUMAN | P48067 | Glycine Transporter 1, Human | 150 | 0.34 | Binding ≤ 1μM |
| SC6A9_HUMAN | P48067 | Glycine Transporter 1, Human | 150 | 0.34 | Binding ≤ 10μM |
| SC6A5_HUMAN | Q9Y345 | Glycine Transporter 2, Human | 5900 | 0.26 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Na+/Cl- dependent neurotransmitter transporters |
