| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| April 13th, 2010 | 29 | Yes |
Popular Name: (2S,4R)-2-amino-4-[3-(2,2-diphenylethylamino)-3-oxo-propyl]pentanedioic (2S,4R)-2-amino-4-[3-(2,2-diphen…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | -0.31 | 9.19 | -75.23 | 4 | 7 | -1 | 137 | 397.451 | 11 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| EAA3-2-E | Excitatory Amino Acid Transporter 3 (cluster #2 Of 2), Eukaryotic | Eukaryotes | 3000 | 0.27 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| EAA3_HUMAN | P43005 | Excitatory Amino Acid Transporter 3, Human | 3000 | 0.27 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Glutamate Neurotransmitter Release Cycle | |
| Transport of inorganic cations/anions and amino acids/oligopeptides |
