In ZINC since | Heavy atoms | Benign functionality |
---|---|---|
April 13th, 2010 | 21 | Yes |
Popular Name: (2S)-1-isopropoxy-3-[[2-(4-methoxyphenyl)-1,1-dimethyl-ethyl]amino]propan-2-ol (2S)-1-isopropoxy-3-[[2-(4-metho…
Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
---|---|---|---|---|---|---|---|---|---|---|
Ref Reference (pH 7) | 2.85 | 4.41 | -43.51 | 3 | 4 | 1 | 55 | 296.431 | 9 | ↓ |
Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
---|---|---|---|---|---|
CASR-1-E | Calcium Sensing Receptor (cluster #1 Of 1), Eukaryotic | Eukaryotes | 10000 | 0.33 | Binding ≤ 10μM |
Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
---|---|---|---|---|---|
CASR_HUMAN | P41180 | Calcium Sensing Receptor, Human | 10000 | 0.33 | Binding ≤ 10μM |
Description | Species |
---|---|
Class C/3 (Metabotropic glutamate/pheromone receptors) | |
G alpha (i) signalling events | |
G alpha (q) signalling events |