| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| April 14th, 2010 | 23 | Yes |
Popular Name: 8-bromo-6-chloro-N-(m-tolyl)-2-oxo-chromene-3-carboxamide 8-bromo-6-chloro-N-(m-tolyl)-2-o…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 4.65 | 9.69 | -9.17 | 1 | 4 | 0 | 59 | 392.636 | 2 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| FA12-1-E | Coagulation Factor XII (cluster #1 Of 1), Eukaryotic | Eukaryotes | 10000 | 0.30 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| FA12_HUMAN | P00748 | Coagulation Factor XII, Human | 10000 | 0.30 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Intrinsic Pathway |
