| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| November 7th, 2005 | 31 | No |
Popular Name: Jervine Jervine
Find On: PubMed — Wikipedia — Google
CAS Numbers: 469-59-0 , [469-59-0]
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 4.38 | -2.72 | -54.39 | 3 | 4 | 1 | 63 | 426.621 | 0 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| SHH-1-E | Sonic Hedgehog Protein (cluster #1 Of 2), Eukaryotic | Eukaryotes | 500 | 0.28 | Binding ≤ 10μM |
| ERG2-1-F | C-8 Sterol Isomerase (cluster #1 Of 2), Fungal | Fungi | 284 | 0.30 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| ERG2_YEAST | P32352 | C-8 Sterol Isomerase, Yeast | 284 | 0.30 | Binding ≤ 1μM |
| SHH_HUMAN | Q15465 | Sonic Hedgehog Protein, Human | 500 | 0.28 | Binding ≤ 1μM |
| ERG2_YEAST | P32352 | C-8 Sterol Isomerase, Yeast | 284 | 0.30 | Binding ≤ 10μM |
| SHH_HUMAN | Q15465 | Sonic Hedgehog Protein, Human | 500 | 0.28 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Class B/2 (Secretin family receptors) | |
| Hedgehog ligand biogenesis | |
| Hh ligand biogenesis disease | |
| Release of Hh-Np from the secreting cell |
