| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| November 26th, 2005 | 27 | Yes |
Popular Name: 2-[1-amino-1-carboxy-2-(9H-xanthen-9-yl)ethyl]-3-methyl-cyclopropane-1-carboxylic 2-[1-amino-1-carboxy-2-(9H-xanth…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 1.36 | -1.07 | -92.18 | 3 | 6 | -1 | 117 | 366.393 | 5 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| GRM3-1-E | Metabotropic Glutamate Receptor 3 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 1000 | 0.31 | Functional ≤ 10μM |
| GRM8-1-E | Metabotropic Glutamate Receptor 8 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 1230 | 0.31 | Functional ≤ 10μM |
| Z50597-1-O | Rattus Norvegicus (cluster #1 Of 5), Other | Other | 71 | 0.37 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| Z50597 | Z50597 | Rattus Norvegicus | 71 | 0.37 | Binding ≤ 1μM |
| Z50597 | Z50597 | Rattus Norvegicus | 71 | 0.37 | Binding ≤ 10μM |
| GRM3_RAT | P31422 | Metabotropic Glutamate Receptor 3, Rat | 1000 | 0.31 | Functional ≤ 10μM |
| GRM8_HUMAN | O00222 | Metabotropic Glutamate Receptor 8, Human | 1230 | 0.31 | Functional ≤ 10μM |
| Description | Species |
|---|---|
| Class C/3 (Metabotropic glutamate/pheromone receptors) | |
| G alpha (i) signalling events |
