| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| July 27th, 2010 | 19 | No |
Popular Name: Ethyl 2-amino-5-(2-chlorophenyl)-4-methylthiophene-3-carboxylate Ethyl 2-amino-5-(2-chlorophenyl)…
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CAS Number: 1213791-75-3
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 4.27 | 7.75 | -8.18 | 2 | 3 | 0 | 52 | 295.791 | 4 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| GRM6-2-E | Metabotropic Glutamate Receptor 6 (cluster #2 Of 2), Eukaryotic | Eukaryotes | 5700 | 0.39 | Functional ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| GRM6_HUMAN | O15303 | Metabotropic Glutamate Receptor 6, Human | 5700 | 0.39 | Functional ≤ 10μM |
| Description | Species |
|---|---|
| Class C/3 (Metabotropic glutamate/pheromone receptors) | |
| G alpha (i) signalling events |
No pre-computed analogs available. Try a structural similarity search.