In ZINC since | Heavy atoms | Benign functionality |
---|---|---|
July 29th, 2010 | 29 | Yes |
Popular Name: 1-[(4-phenylphenyl)methyl]-6-(trifluoromethoxy)indoline-2,3-dione 1-[(4-phenylphenyl)methyl]-6-(tr…
None
Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
---|---|---|---|---|---|---|---|---|---|---|
Ref Reference (pH 7) | 5.23 | 11.11 | -10.29 | 0 | 4 | 0 | 48 | 397.352 | 5 | ↓ |
Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
---|---|---|---|---|---|
ACM5-1-E | Muscarinic Acetylcholine Receptor M5 (cluster #1 Of 3), Eukaryotic | Eukaryotes | 2700 | 0.27 | Functional ≤ 10μM |
Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
---|---|---|---|---|---|
ACM5_HUMAN | P08912 | Muscarinic Acetylcholine Receptor M5, Human | 2700 | 0.27 | Functional ≤ 10μM |
Description | Species |
---|---|
G alpha (q) signalling events | |
Muscarinic acetylcholine receptors |